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Center for Physical Genomics and Engineering

A new physics-based approach to reprogramming the genome to treat disease

About the Center

Through a combination of breakthrough optical imaging and computational genomics, the Center for Physical Genomics and Engineering (CPGE) focuses on reprogramming the genome's chromatin, which regulates gene expression, in order to treat disease and engineer living systems to overcome environmental challenges.

The Center for Physical Genomics and Engineering is part of the McCormick School of Engineering.



Center Launch Event

Symposium on Physical Genomics

Join us for the launch event for the Center for Physical Genomics and Engineering.

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Our Strengths


Learn about the research that focuses on controlling gene expression with impact ranging from disease treatment to climate change management.
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Discover mentorship programs, symposia, and opportunities for gaining practical experience available to graduate students and postdoctoral researchers.
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Knowledge Transfer

Find out how the center trains the next generation of scientists and engineers through cross-disciplinary platforms.

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What is Physical Genomics?

Physical genomics is a new field that involves understanding the structure, function, and fundamental principles of the genome. With this understanding, researchers can reversibly regulate, control, and even reprogram global patterns of gene expression.

The Next Frontier in Biological Discovery

"The impact of this emerging field could be widespread: ranging from treating diseases to improving crop yields and mitigating the impact of climate change on plants."

-- Vadim Backman, Director of Center for Physical Genomics and Engineering

News & Events



Whole-Brain Leadership for PhD Students Seminar Series: Ken Alder

April 17
12:00 PM - 1:00 PM

Segal Design Leadership Series presents: Design and Strategy: Wha...

April 17
4:00 PM - 5:00 PM

BME Seminar Series: Ngan Huang, PhD

April 18
4:00 PM - 5:00 PM

TEAM/SDRC Seminar: New Directions in Ovarian Cancer Metastasis

April 19
12:00 PM - 1:00 PM

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